An perspective: Potential medicinal plant resources for filariasis disease.

Abstract

Filariasis is one of the oldest and most debilitating neglected tropical diseases, which is caused by parasitic filarial worm that are transmitted to humans by mosquitoes. In the lymphatics system filarial worm become adult worm that cause damage to lymphatics resulting in dilatation of lymph vessels. An estimated approximately 120 million people in 83 countries. An estimated approximately one and half billion live in areas where filariasis is endemic and are at risk of infection with Wuchereria bancrofti, Brugia timori and Brugia malayi. Presently diethylcarbamazine and Ivermectin and a single-dose treatment are currently employing in an attempt to control the infection but these drugs cannot treat properly and have lots of side effects. Recently limited plant products were reported to be beneficial in the treatment or control of these parasitic infections like filariasis but they could not be developed into viable drugs for a variety of reasons. This review focuses on searching medicinal plants for filariasis diseases.  In this review, we explored medicinal plant that show the anti-filarial activities on filarial worm. These medical plants will help for further development the potation drug development for the treatment